A database of hormones and their receptors

Home

Hormone Peptide Non-peptide Search Search Browse Browse H-R Pair H-R Pair

Receptor Search Browse

Tools BLAST Domain Search Peptide Mapping Structure Search

Miscellaneous Online Submission HMRbase Information Supplementary Information Recent Information Help

Contact

Peptide Hormone

Search Result - 1

HMRbase accession number	10125
Swiss-prot Accession number	Q2Q1P2 (Sequence in FASTA format)
Description	Lutropin subunit beta precursor (Luteinizing hormone subunit beta)(LSH-beta) (LSH-B) (LH-B) (Lutropin beta chain).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the glycoprotein hormones subunit beta family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids
Protein Length	141 Amino acids
Molecular weight	15333
References	1   Hallast P., Rull K., Laan M.; "What is the evidence for the functionality of CGB1 and CGB2?"; Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
Domain Name	Cys_knot
Hormone Name	Luteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
Mature Hormone Sequence	SREPLRPWCHPINATLAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL
Position of mature hormone in Pre-Hormone protein	121 Residues from position (21-141)
Receptor	N/A
Gene ID	468950
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	10207
Swiss-prot Accession number	Q2PUH2 (Sequence in FASTA format)
Description	Follitropin subunit beta precursor (Follicle-stimulating hormone betasubunit) (FSH-beta) (FSH-B) (Follitropin beta chain).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glycoprotein hormones subunit beta family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Stimulates development of follicle and spermatogenesis in the reproductive organs
Protein Length	129 Amino acids
Molecular weight	14660
References	1   Grigorova M., Laan M.; "FSHB gene has two major haplotypes."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 2   Grigorova M., Laan M.; "FSHB gene has two major haplotypes."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
Domain Name	Cys_knot
Hormone Name	Follicle-stimulating hormone beta subunit
Mature Hormone Sequence	CELTNITIAIEKEECRFCISINTTWCAGHCYTRDLVYKDPARPNIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE
Position of mature hormone in Pre-Hormone protein	109 Residues from position (21-129)
Receptor	N/A
Gene ID	736618
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	10288
Swiss-prot Accession number	Q5CZK2 (Sequence in FASTA format)
Description	Relaxin-3 precursor (Prorelaxin H3) [Contains: Relaxin-3 B chain;Relaxin-3 A chain].
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)
Protein Length	142 Amino acids
Molecular weight	15348
References	1  PubMed abstract 16136131 2  PubMed abstract 15707501
Domain Name	Insulin
Hormone Name	Relaxin-3 B chain
Mature Hormone Sequence	RAAPYGVRLCGREFIRAVIFTCGGSRW
Position of mature hormone in Pre-Hormone protein	27 Residues from position (26-52)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	10289
Swiss-prot Accession number	Q5CZK2 (Sequence in FASTA format)
Description	Relaxin-3 precursor (Prorelaxin H3) [Contains: Relaxin-3 B chain;Relaxin-3 A chain].
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)
Protein Length	142 Amino acids
Molecular weight	15348
References	1  PubMed abstract 16136131 2  PubMed abstract 15707501
Domain Name	Insulin
Hormone Name	Relaxin-3 A chain
Mature Hormone Sequence	DVLAGLSSSCCKWGCSKSEISSLC
Position of mature hormone in Pre-Hormone protein	24 Residues from position (119-142)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	10710
Swiss-prot Accession number	P58757 (Sequence in FASTA format)
Description	Growth hormone variant precursor (GH-V) (Placenta-specific growthhormone) (Growth hormone 2).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the somatotropin/prolactin family.
Tissue Specificity	Expressed in the placenta
Post translational modification	N/A
Function	Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length	217 Amino acids
Molecular weight	24991
References	1   Revol A., Esquivel D., Santiago D., Barrera-Saldana H.; "Independent duplication of the growth hormone gene in threeAnthropoidean lineages."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Domain Name	Hormone_1
Hormone Name	Growth hormone variant
Mature Hormone Sequence	FPTIPLSRLFDNAMLRAHRLYQLAYDTYQEFEEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
Position of mature hormone in Pre-Hormone protein	191 Residues from position (27-217)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	10757
Swiss-prot Accession number	P58756 (Sequence in FASTA format)
Description	Somatotropin precursor (Growth hormone) (GH) (GH-N) (Pituitary growthhormone) (Growth hormone 1).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the somatotropin/prolactin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length	217 Amino acids
Molecular weight	24843
References	1   Revol A., Esquivel D., Santiago D., Barrera-Saldana H.; "Independent duplication of the growth hormone gene in threeAnthropoidean lineages."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Domain Name	Hormone_1
Hormone Name	Somatotropin
Mature Hormone Sequence	FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
Position of mature hormone in Pre-Hormone protein	191 Residues from position (27-217)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	10873
Swiss-prot Accession number	P30410 (Sequence in FASTA format)
Description	Insulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length	110 Amino acids
Molecular weight	12025
References	1  PubMed abstract 1560757 2  PubMed abstract 12952878
Domain Name	Insulin
Hormone Name	Insulin B chain
Mature Hormone Sequence	FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Position of mature hormone in Pre-Hormone protein	30 Residues from position (25-54)
Receptor	N/A
Gene ID	449570
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 8

HMRbase accession number	10874
Swiss-prot Accession number	P30410 (Sequence in FASTA format)
Description	Insulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length	110 Amino acids
Molecular weight	12025
References	1  PubMed abstract 1560757 2  PubMed abstract 12952878
Domain Name	Insulin
Hormone Name	Insulin A chain
Mature Hormone Sequence	GIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein	21 Residues from position (90-110)
Receptor	N/A
Gene ID	449570
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 9

HMRbase accession number	11208
Swiss-prot Accession number	P51454 (Sequence in FASTA format)
Description	Prorelaxin H1 precursor [Contains: Relaxin B chain; Relaxin A chain](Fragment).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	Expressed in the corpus luteum of pregnancy but not in the placenta
Post translational modification	N/A
Function	Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length	166 Amino acids
Molecular weight	18731
References	1  PubMed abstract 8182365
Domain Name	Insulin
Hormone Name	Relaxin B chain
Mature Hormone Sequence	DSWMDEVIKLCGRELVRAQIAICGMSTWS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (6-34)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 10

HMRbase accession number	11209
Swiss-prot Accession number	P51454 (Sequence in FASTA format)
Description	Prorelaxin H1 precursor [Contains: Relaxin B chain; Relaxin A chain](Fragment).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	Expressed in the corpus luteum of pregnancy but not in the placenta
Post translational modification	N/A
Function	Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length	166 Amino acids
Molecular weight	18731
References	1  PubMed abstract 8182365
Domain Name	Insulin
Hormone Name	Relaxin A chain
Mature Hormone Sequence	QPYVALFEKCCLIGCTKRSLANYC
Position of mature hormone in Pre-Hormone protein	24 Residues from position (143-166)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 11

HMRbase accession number	11212
Swiss-prot Accession number	P51455 (Sequence in FASTA format)
Description	Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain](Fragment).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	Expressed in the corpus luteum of pregnancy and in the placenta
Post translational modification	N/A
Function	Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length	166 Amino acids
Molecular weight	18761
References	1  PubMed abstract 8182365 2  PubMed abstract 8735594
Domain Name	Insulin
Hormone Name	Relaxin B chain
Mature Hormone Sequence	DSWMDEVIKLCGRELVRAQIAICGKSTWS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (6-34)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 12

HMRbase accession number	11213
Swiss-prot Accession number	P51455 (Sequence in FASTA format)
Description	Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain](Fragment).
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	Expressed in the corpus luteum of pregnancy and in the placenta
Post translational modification	N/A
Function	Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length	166 Amino acids
Molecular weight	18761
References	1  PubMed abstract 8182365 2  PubMed abstract 8735594
Domain Name	Insulin
Hormone Name	Relaxin A chain
Mature Hormone Sequence	QLYSALANKCCHVGCTKRSLARFC
Position of mature hormone in Pre-Hormone protein	24 Residues from position (143-166)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 13

HMRbase accession number	11535
Swiss-prot Accession number	O02750 (Sequence in FASTA format)
Description	Leptin;Alternative Name: Obesity factor
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted (Probable)
Developmental Stage	N/A
Similarity	Belongs to the leptin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass (By similarity).
Protein Length	146 Amino acids
Molecular weight	16059
References	----
Domain Name	Leptin
Hormone Name	Leptin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 14

HMRbase accession number	11578
Swiss-prot Accession number	P60016 (Sequence in FASTA format)
Description	Renin; EC=3.4.23.15;Alternative Name: Angiotensinogenase;Precursor
Source organism	Pan troglodytes (Chimpanzee)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular location	Secreted (By similarity). Membrane (By similarity). Note=Associated to membranes via binding to ATP6AP2 (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the peptidase A1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney (By similarity).
Protein Length	406 Amino acids
Molecular weight	45057
References	1  PubMed abstract 11013071
Domain Name	A1_Propeptide  Asp
Hormone Name	Renin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
Receptor	N/A
Gene ID	469651
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated